Prediction of Simultaneous Heart Kidney Allocation and Post-Transplant Adverse Kidney Outcomes |
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Lab Values at the time of wait listing |
Estimated glomerular filtration rate(eGFR)§: |
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ml/min/1.73 m² |
eGFR reported more than one month prior: |
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ml/min/1.73 m²
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eGFR ratio (previous / current): |
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|
Blood urea nitrogen (BUN): |
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mg/dL |
Brain Natriuretic Peptide:
N-terminal pro b-type Natriuretic Peptide (NT-proBNP):
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pg/mL |
RHC measurements at the time of wait listing |
Central venous pressure (CVP): |
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mmHg |
Pulmonary artery mean pressure (PAMP): |
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mmHg |
Pulmonary Capillary Wedge Pressure (PCWP): |
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mmHg |
Cardiac Index (CI): |
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L/min/m² |
Problem list at the time of wait listing |
Dialysis status: |
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Yes
No |
Dialysis required more than one month prior: |
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Yes
No |
Diabetes status: |
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No diabetes
Type I
Type II |
Heart failure diagnosis: |
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Nonischemic dilated cardiomyopathy (CM)
Ischemic CM
Restrictive CM including amyloid
Hypertrophic CM
Congenital anomalies
Failed heart allograft
Other diagnosis including valvular heart diseases |
Number of previous heart transplants: |
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0
1
2 |
Heart allocation |
The New Heart Allocation Status (6-tier): |
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1
2
3
4
5
6 |
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|
|
|
|
|
|
|
|
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This calculator uses a random forest classifier and correctly classifies patients with the composite outcome who needs simultaneous heart kidney transplant (SHK) allocation and/or at risk of developing advanced kidney failure within first year of heart transplantation with C-statistic = 84.9%, Sensitivity = 60.5%, Specificity = 94.2%, NPV = 94.0%, and PPV = 61.8%.
Laboratory values and right heart catheterization measurements are typically reported within seven days of each other.
*Advanced kidney failure is defined as dependence on chronic dialysis, eGFR < 20 ml/min/1.73 m² or received a kidney transplantation within first year of transplant among adult heart transplant recipients.
§eGFR is calculated based on new CKD-EPI 2021 creatinine equations that do not include a race coefficient.
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| This calculator is published as a part of https://doi.org/10.1016/j.ekir.2025.10.005. |